Harvard Skin Disease Research Center
Harvard Institutes of Medicine, Room 664
77 Avenue Louis Pasteur
Boston, MA 02115
Lab Website: http://dimitrofflab.bwh.harvard.edu/
Charles J. Dimitroff, Ph.D.
Associate Professor of Dermatology
Associate Director for Laboratory Research
Brigham and Women’s Hospital
Department of Dermatology
Harvard Medical School
Ph.D. Program in Immunology
Division of Medical Sciences
Harvard U. Graduate School of Arts & Sciences
THE GLYCOBIOLOGY OF
CANCER AND IMMUNOLOGY
DEPARTMENT OF DERMATOLOGY
BRIGHAM AND WOMEN’S HOSPITAL
HARVARD MEDICAL SCHOOL
The Laboratory of Dr. Charles J Dimitroff in the Department of Dermatology at Brigham and Women’s Hospital (BWH) in Boston is seeking a post-doctoral fellow with experience in studies on cancer and/or immunology. The long-term research goals of the Laboratory are to identify glycobiological regulators of cancer progression and of adaptive immune responses. While prior experience in glycobiology studies are not essential, the successful candidate will investigate how melanoma cell glycans and related glycan-binding lectins impact growth and metastasis; or, similarly, how lymphocyte glycans/lectins regulate their fate and function. These research projects utilize both in vitro methods: IF/IHC, flow cytometry/cell sorting analysis, RT-qPCR, gene expression analysis, western blotting, lectin-affinity chromatography and ex vivo cell isolation/culturing, as well as in vivo methods: human tumor xenograft growth and metastasis, syngeneic murine melanoma growth/metastasis assays and murine models of adaptive immunity. In all, Dr. Dimitroff seeks a candidate who wants to conduct translational studies that can quickly and directly impact patient care. Highly-motivated candidates with an M.D., Ph.D., or M.D./Ph.D. and experience in conducting studies on cancer progression or on the development of adaptive immunity are strongly encouraged to apply. Applicants should possess strong laboratory, analytical, interpersonal and communication skills. Prior work with human cells and/or mouse models is necessary.
The BWH Department of Dermatology is located in the Longwood Medical Area, which contains ten major institutions, including research-oriented hospitals, research institutes, Harvard Medical School, and the Harvard School of Public Health, to provide a rich training environment. Interested candidates should email a brief cover letter indicating their research interests and career goals, CV, and contact information for 3 references to:
Attn: Matthew Opperman; MOPPERMAN@BWH.HARVARD.EDU
An Equal Opportunity / Affirmative Action Employer.