Sylvain Lehoux, Ph.D.
National Center for Functional Glycomics
Beth Israel Deaconess Medical Center, Harvard Medical School
Dr. Lehoux graduated from the University of Science and Technologies of Lille (France) under the mentorship of Prof. Philippe Delannoy and Dr. Marie-Krzewinsky-Recchi. His PhD work focused on the transcriptional regulation the sialyltransferase ST6Gal2 in human brain and neuronal cells. In 2010, he moved to Dr. Cummings' lab for a post-doctoral position at Emory University, Atlanta where he studied the structure and role of abnormal O-glycans in the hinge region of IgA1 in the context of the autoimmune disease IgA Nephropathy. His work notably revealed that IgA1 of healthy individuals carries the Tn antigen and that two distinct glycoforms of IgA1 can be chromatographically separated.
In 2015, following his post-doctoral fellowship, Dr. Lehoux became Research Project Manager and was part of the Cummings group move from Emory University to Beth Israel Deaconess Medical Center in Boston. With regard to the NCFG activities, Dr. Lehoux more particularly took charge of collaborative projects, especially with research groups at BIDMC and within the greater Boston area. In addition, he assists and supervises visiting collaborators, new personnel and post-doctoral fellows joining the lab.
Dr. Lehoux is also the Director of the BIDMC Glycomics Core whose goals are to provide services and expertise in the field of glycobiology.